Rationale and design of MUSIC OS-EU: an international observational study of the treatment of postmenopausal women for osteoporosis in Europe and Canada.
Identifieur interne : 000D04 ( Main/Exploration ); précédent : 000D03; suivant : 000D05Rationale and design of MUSIC OS-EU: an international observational study of the treatment of postmenopausal women for osteoporosis in Europe and Canada.
Auteurs : Ankita Modi [États-Unis] ; Shuvayu Sen [États-Unis] ; Jonathan D. Adachi [Canada] ; Silvano Adami [Italie] ; Bernard Cortet [France] ; Alun L. Cooper [Royaume-Uni] ; Piet Geusens [Pays-Bas] ; Dan Mellström [Suède] ; Jessica P. Weaver [États-Unis] ; Joop P. Van Den Bergh [Pays-Bas] ; Allison M. Nguyen [États-Unis] ; Paul A. Keown [Canada] ; Albert T. Leung [États-Unis] ; Shiva Sajjan [États-Unis]Source :
- Clinical and experimental rheumatology [ 0392-856X ]
Descripteurs français
- KwdFr :
- Adhésion au traitement médicamenteux (MeSH), Adulte d'âge moyen (MeSH), Agents de maintien de la densité osseuse (administration et posologie), Agents de maintien de la densité osseuse (effets indésirables), Canada (épidémiologie), Coopération internationale (MeSH), Enquêtes et questionnaires (MeSH), Europe (épidémiologie), Femelle (MeSH), Humains (MeSH), Maladies gastro-intestinales (induit chimiquement), Maladies gastro-intestinales (épidémiologie), Ostéoporose post-ménopausique (diagnostic), Ostéoporose post-ménopausique (psychologie), Ostéoporose post-ménopausique (traitement médicamenteux), Prise en charge de la maladie (MeSH), Qualité de vie (MeSH), Satisfaction des patients (MeSH), Sujet âgé (MeSH), Types de pratiques des médecins (MeSH), Études de cohortes (MeSH), Études prospectives (MeSH).
- MESH :
- administration et posologie : Agents de maintien de la densité osseuse.
- diagnostic : Ostéoporose post-ménopausique.
- effets indésirables : Agents de maintien de la densité osseuse.
- induit chimiquement : Maladies gastro-intestinales.
- psychologie : Ostéoporose post-ménopausique.
- traitement médicamenteux : Ostéoporose post-ménopausique.
- épidémiologie : Canada, Europe, Maladies gastro-intestinales.
- Adhésion au traitement médicamenteux, Adulte d'âge moyen, Coopération internationale, Enquêtes et questionnaires, Femelle, Humains, Prise en charge de la maladie, Qualité de vie, Satisfaction des patients, Sujet âgé, Types de pratiques des médecins, Études de cohortes, Études prospectives.
- Wicri :
- geographic : Canada.
English descriptors
- KwdEn :
- Aged (MeSH), Bone Density Conservation Agents (administration & dosage), Bone Density Conservation Agents (adverse effects), Canada (epidemiology), Cohort Studies (MeSH), Disease Management (MeSH), Europe (epidemiology), Female (MeSH), Gastrointestinal Diseases (chemically induced), Gastrointestinal Diseases (epidemiology), Humans (MeSH), International Cooperation (MeSH), Medication Adherence (MeSH), Middle Aged (MeSH), Osteoporosis, Postmenopausal (diagnosis), Osteoporosis, Postmenopausal (drug therapy), Osteoporosis, Postmenopausal (psychology), Patient Satisfaction (MeSH), Practice Patterns, Physicians' (MeSH), Prospective Studies (MeSH), Quality of Life (MeSH), Surveys and Questionnaires (MeSH).
- MESH :
- chemical , administration & dosage : Bone Density Conservation Agents.
- chemical , adverse effects : Bone Density Conservation Agents.
- geographic , epidemiology : Canada, Europe.
- chemically induced : Gastrointestinal Diseases.
- diagnosis : Osteoporosis, Postmenopausal.
- drug therapy : Osteoporosis, Postmenopausal.
- epidemiology : Gastrointestinal Diseases.
- psychology : Osteoporosis, Postmenopausal.
- Aged, Cohort Studies, Disease Management, Female, Humans, International Cooperation, Medication Adherence, Middle Aged, Patient Satisfaction, Practice Patterns, Physicians', Prospective Studies, Quality of Life, Surveys and Questionnaires.
Abstract
OBJECTIVES
The Medication Use Patterns, Treatment Satisfaction, and Inadequate Control of Osteoporosis Study (MUSIC OS-EU) was designed to better understand the rate and burden of gastrointestinal (GI) events on clinical and health care outcomes among postmenopausal women with osteoporosis.
METHODS
MUSIC OS-EU is a prospective, multinational, observational cohort study of postmenopausal women ≥50 years of age diagnosed with osteoporosis and enrolled in physician clinics in six countries: France, Italy, the Netherlands, Sweden, the United Kingdom, and Canada. The MUSIC OS-EU study has three components: (i) a physician survey to describe their management of osteoporotic patients with GI events; (ii) a retrospective chart survey to describe the receipt and type of osteoporosis medication prescribed; and (iii) a prospective cohort study including untreated and treated patients diagnosed with osteoporosis to investigate the rate of GI events and association with osteoporosis medication use patterns, health-related quality of life, treatment satisfaction and resource utilisation among postmenopausal women with osteoporosis.
RESULTS
Physicians at 97 sites completed the physician questionnaire and data for 716 patients were abstracted for the retrospective chart review. Enrolment and the baseline data collection for the prospective cohort study were conducted between March 2012 and June 2013 for 292 untreated and 2,959 treated patients, of whom 684 were new users and 2,275 were experienced users of oral osteoporosis medications.
CONCLUSIONS
The results of MUSIC OS-EU will illuminate the association of GI events with the management of osteoporosis and with patient-reported outcomes among postmenopausal women with osteoporosis in Europe and Canada.
PubMed: 26146786
Affiliations:
- Canada, France, Italie, Pays-Bas, Royaume-Uni, Suède, États-Unis
- Colombie-Britannique, New Jersey
- Vancouver
Links toward previous steps (curation, corpus...)
Le document en format XML
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Adachi</name><affiliation wicri:level="1"><nlm:affiliation>St. Joseph's Healthcare and McMaster University, Hamilton, Ontario, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>St. Joseph's Healthcare and McMaster University, Hamilton, Ontario</wicri:regionArea><wicri:noRegion>Ontario</wicri:noRegion></affiliation></author><author><name sortKey="Adami, Silvano" sort="Adami, Silvano" uniqKey="Adami S" first="Silvano" last="Adami">Silvano Adami</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medicine, University of Verona, Verona, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Department of Medicine, University of Verona, Verona</wicri:regionArea><wicri:noRegion>Verona</wicri:noRegion></affiliation></author><author><name sortKey="Cortet, Bernard" sort="Cortet, Bernard" uniqKey="Cortet B" first="Bernard" last="Cortet">Bernard Cortet</name><affiliation wicri:level="1"><nlm:affiliation>Department of Rheumatology, University Hospital of Lille, Lille Cedex, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Department of Rheumatology, University Hospital of Lille, Lille Cedex</wicri:regionArea><wicri:noRegion>Lille Cedex</wicri:noRegion><wicri:noRegion>Lille Cedex</wicri:noRegion></affiliation></author><author><name sortKey="Cooper, Alun L" sort="Cooper, Alun L" uniqKey="Cooper A" first="Alun L" last="Cooper">Alun L. Cooper</name><affiliation wicri:level="1"><nlm:affiliation>Bridge Medical Centre Crawley, West Sussex, UK.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Bridge Medical Centre Crawley, West Sussex</wicri:regionArea><wicri:noRegion>West Sussex</wicri:noRegion></affiliation></author><author><name sortKey="Geusens, Piet" sort="Geusens, Piet" uniqKey="Geusens P" first="Piet" last="Geusens">Piet Geusens</name><affiliation wicri:level="1"><nlm:affiliation>Department of Rheumatology, CAPHRI School for Public Health and Primary Care, Maastricht University, Maastricht, the Netherlands.</nlm:affiliation><country xml:lang="fr" wicri:curation="lc">Pays-Bas</country><wicri:regionArea>Department of Rheumatology, CAPHRI School for Public Health and Primary Care, Maastricht University, Maastricht</wicri:regionArea><wicri:noRegion>Maastricht</wicri:noRegion></affiliation></author><author><name sortKey="Mellstrom, Dan" sort="Mellstrom, Dan" uniqKey="Mellstrom D" first="Dan" last="Mellström">Dan Mellström</name><affiliation wicri:level="1"><nlm:affiliation>Department of Internal Medicine and Geriatrics, Gothenburg University, Göteborg, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Internal Medicine and Geriatrics, Gothenburg University, Göteborg</wicri:regionArea><wicri:noRegion>Göteborg</wicri:noRegion></affiliation></author><author><name sortKey="Weaver, Jessica P" sort="Weaver, Jessica P" uniqKey="Weaver J" first="Jessica P" last="Weaver">Jessica P. Weaver</name><affiliation wicri:level="2"><nlm:affiliation>Merck & Co., Inc., Kenilworth, New Jersey, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Merck & Co., Inc., Kenilworth, New Jersey</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Van Den Bergh, Joop P" sort="Van Den Bergh, Joop P" uniqKey="Van Den Bergh J" first="Joop P" last="Van Den Bergh">Joop P. Van Den Bergh</name><affiliation wicri:level="1"><nlm:affiliation>VieCuri Medical Centre, Venlo, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>VieCuri Medical Centre, Venlo</wicri:regionArea><wicri:noRegion>Venlo</wicri:noRegion></affiliation></author><author><name sortKey="Nguyen, Allison M" sort="Nguyen, Allison M" uniqKey="Nguyen A" first="Allison M" last="Nguyen">Allison M. Nguyen</name><affiliation wicri:level="2"><nlm:affiliation>Merck & Co., Inc., Kenilworth, New Jersey, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Merck & Co., Inc., Kenilworth, New Jersey</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Keown, Paul A" sort="Keown, Paul A" uniqKey="Keown P" first="Paul A" last="Keown">Paul A. Keown</name><affiliation wicri:level="3"><nlm:affiliation>Syreon Corporation, Vancouver, Canada.</nlm:affiliation><country xml:lang="fr">Canada</country><wicri:regionArea>Syreon Corporation, Vancouver</wicri:regionArea><placeName><settlement type="city">Vancouver</settlement><region type="state">Colombie-Britannique</region></placeName></affiliation></author><author><name sortKey="Leung, Albert T" sort="Leung, Albert T" uniqKey="Leung A" first="Albert T" last="Leung">Albert T. Leung</name><affiliation wicri:level="2"><nlm:affiliation>Former employee of Merck & Co., Inc., Kenilworth, New Jersey, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Former employee of Merck & Co., Inc., Kenilworth, New Jersey</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author><author><name sortKey="Sajjan, Shiva" sort="Sajjan, Shiva" uniqKey="Sajjan S" first="Shiva" last="Sajjan">Shiva Sajjan</name><affiliation wicri:level="2"><nlm:affiliation>Merck & Co., Inc., Kenilworth, New Jersey, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Merck & Co., Inc., Kenilworth, New Jersey</wicri:regionArea><placeName><region type="state">New Jersey</region></placeName></affiliation></author></analytic><series><title level="j">Clinical and experimental rheumatology</title><idno type="ISSN">0392-856X</idno></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged (MeSH)</term><term>Bone Density Conservation Agents (administration & dosage)</term><term>Bone Density Conservation Agents (adverse effects)</term><term>Canada (epidemiology)</term><term>Cohort Studies (MeSH)</term><term>Disease Management (MeSH)</term><term>Europe (epidemiology)</term><term>Female (MeSH)</term><term>Gastrointestinal Diseases (chemically induced)</term><term>Gastrointestinal Diseases (epidemiology)</term><term>Humans (MeSH)</term><term>International Cooperation (MeSH)</term><term>Medication Adherence (MeSH)</term><term>Middle Aged (MeSH)</term><term>Osteoporosis, Postmenopausal (diagnosis)</term><term>Osteoporosis, Postmenopausal (drug therapy)</term><term>Osteoporosis, Postmenopausal (psychology)</term><term>Patient Satisfaction (MeSH)</term><term>Practice Patterns, Physicians' (MeSH)</term><term>Prospective Studies (MeSH)</term><term>Quality of Life (MeSH)</term><term>Surveys and Questionnaires (MeSH)</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adhésion au traitement médicamenteux (MeSH)</term><term>Adulte d'âge moyen (MeSH)</term><term>Agents de maintien de la densité osseuse (administration et posologie)</term><term>Agents de maintien de la densité osseuse (effets indésirables)</term><term>Canada (épidémiologie)</term><term>Coopération internationale (MeSH)</term><term>Enquêtes et questionnaires (MeSH)</term><term>Europe (épidémiologie)</term><term>Femelle (MeSH)</term><term>Humains (MeSH)</term><term>Maladies gastro-intestinales (induit chimiquement)</term><term>Maladies gastro-intestinales (épidémiologie)</term><term>Ostéoporose post-ménopausique (diagnostic)</term><term>Ostéoporose post-ménopausique (psychologie)</term><term>Ostéoporose post-ménopausique (traitement médicamenteux)</term><term>Prise en charge de la maladie (MeSH)</term><term>Qualité de vie (MeSH)</term><term>Satisfaction des patients (MeSH)</term><term>Sujet âgé (MeSH)</term><term>Types de pratiques des médecins (MeSH)</term><term>Études de cohortes (MeSH)</term><term>Études prospectives (MeSH)</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Bone Density Conservation Agents</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Bone Density Conservation Agents</term></keywords><keywords scheme="MESH" type="geographic" qualifier="epidemiology" xml:lang="en"><term>Canada</term><term>Europe</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Agents de maintien de la densité osseuse</term></keywords><keywords scheme="MESH" qualifier="chemically induced" xml:lang="en"><term>Gastrointestinal Diseases</term></keywords><keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Osteoporosis, Postmenopausal</term></keywords><keywords scheme="MESH" qualifier="diagnostic" xml:lang="fr"><term>Ostéoporose post-ménopausique</term></keywords><keywords scheme="MESH" qualifier="drug therapy" xml:lang="en"><term>Osteoporosis, Postmenopausal</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Agents de maintien de la densité osseuse</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Gastrointestinal Diseases</term></keywords><keywords scheme="MESH" qualifier="induit chimiquement" xml:lang="fr"><term>Maladies gastro-intestinales</term></keywords><keywords scheme="MESH" qualifier="psychologie" xml:lang="fr"><term>Ostéoporose post-ménopausique</term></keywords><keywords scheme="MESH" qualifier="psychology" xml:lang="en"><term>Osteoporosis, Postmenopausal</term></keywords><keywords scheme="MESH" qualifier="traitement médicamenteux" xml:lang="fr"><term>Ostéoporose post-ménopausique</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Canada</term><term>Europe</term><term>Maladies gastro-intestinales</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Cohort Studies</term><term>Disease Management</term><term>Female</term><term>Humans</term><term>International Cooperation</term><term>Medication Adherence</term><term>Middle Aged</term><term>Patient Satisfaction</term><term>Practice Patterns, Physicians'</term><term>Prospective Studies</term><term>Quality of Life</term><term>Surveys and Questionnaires</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adhésion au traitement médicamenteux</term><term>Adulte d'âge moyen</term><term>Coopération internationale</term><term>Enquêtes et questionnaires</term><term>Femelle</term><term>Humains</term><term>Prise en charge de la maladie</term><term>Qualité de vie</term><term>Satisfaction des patients</term><term>Sujet âgé</term><term>Types de pratiques des médecins</term><term>Études de cohortes</term><term>Études prospectives</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Canada</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p><b>OBJECTIVES</b></p><p>The Medication Use Patterns, Treatment Satisfaction, and Inadequate Control of Osteoporosis Study (MUSIC OS-EU) was designed to better understand the rate and burden of gastrointestinal (GI) events on clinical and health care outcomes among postmenopausal women with osteoporosis.</p></div><div type="abstract" xml:lang="en"><p><b>METHODS</b></p><p>MUSIC OS-EU is a prospective, multinational, observational cohort study of postmenopausal women ≥50 years of age diagnosed with osteoporosis and enrolled in physician clinics in six countries: France, Italy, the Netherlands, Sweden, the United Kingdom, and Canada. The MUSIC OS-EU study has three components: (i) a physician survey to describe their management of osteoporotic patients with GI events; (ii) a retrospective chart survey to describe the receipt and type of osteoporosis medication prescribed; and (iii) a prospective cohort study including untreated and treated patients diagnosed with osteoporosis to investigate the rate of GI events and association with osteoporosis medication use patterns, health-related quality of life, treatment satisfaction and resource utilisation among postmenopausal women with osteoporosis.</p></div><div type="abstract" xml:lang="en"><p><b>RESULTS</b></p><p>Physicians at 97 sites completed the physician questionnaire and data for 716 patients were abstracted for the retrospective chart review. Enrolment and the baseline data collection for the prospective cohort study were conducted between March 2012 and June 2013 for 292 untreated and 2,959 treated patients, of whom 684 were new users and 2,275 were experienced users of oral osteoporosis medications.</p></div><div type="abstract" xml:lang="en"><p><b>CONCLUSIONS</b></p><p>The results of MUSIC OS-EU will illuminate the association of GI events with the management of osteoporosis and with patient-reported outcomes among postmenopausal women with osteoporosis in Europe and Canada.</p></div></front></TEI><pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">26146786</PMID><DateCompleted><Year>2015</Year><Month>10</Month><Day>02</Day></DateCompleted><DateRevised><Year>2017</Year><Month>01</Month><Day>12</Day></DateRevised><Article PubModel="Print-Electronic"><Journal><ISSN IssnType="Print">0392-856X</ISSN><JournalIssue CitedMedium="Print"><Volume>33</Volume><Issue>4</Issue><PubDate><MedlineDate>2015 Jul-Aug</MedlineDate></PubDate></JournalIssue><Title>Clinical and experimental rheumatology</Title><ISOAbbreviation>Clin Exp Rheumatol</ISOAbbreviation></Journal><ArticleTitle>Rationale and design of MUSIC OS-EU: an international observational study of the treatment of postmenopausal women for osteoporosis in Europe and Canada.</ArticleTitle><Pagination><MedlinePgn>537-44</MedlinePgn></Pagination><Abstract><AbstractText Label="OBJECTIVES" NlmCategory="OBJECTIVE">The Medication Use Patterns, Treatment Satisfaction, and Inadequate Control of Osteoporosis Study (MUSIC OS-EU) was designed to better understand the rate and burden of gastrointestinal (GI) events on clinical and health care outcomes among postmenopausal women with osteoporosis.</AbstractText><AbstractText Label="METHODS" NlmCategory="METHODS">MUSIC OS-EU is a prospective, multinational, observational cohort study of postmenopausal women ≥50 years of age diagnosed with osteoporosis and enrolled in physician clinics in six countries: France, Italy, the Netherlands, Sweden, the United Kingdom, and Canada. The MUSIC OS-EU study has three components: (i) a physician survey to describe their management of osteoporotic patients with GI events; (ii) a retrospective chart survey to describe the receipt and type of osteoporosis medication prescribed; and (iii) a prospective cohort study including untreated and treated patients diagnosed with osteoporosis to investigate the rate of GI events and association with osteoporosis medication use patterns, health-related quality of life, treatment satisfaction and resource utilisation among postmenopausal women with osteoporosis.</AbstractText><AbstractText Label="RESULTS" NlmCategory="RESULTS">Physicians at 97 sites completed the physician questionnaire and data for 716 patients were abstracted for the retrospective chart review. Enrolment and the baseline data collection for the prospective cohort study were conducted between March 2012 and June 2013 for 292 untreated and 2,959 treated patients, of whom 684 were new users and 2,275 were experienced users of oral osteoporosis medications.</AbstractText><AbstractText Label="CONCLUSIONS" NlmCategory="CONCLUSIONS">The results of MUSIC OS-EU will illuminate the association of GI events with the management of osteoporosis and with patient-reported outcomes among postmenopausal women with osteoporosis in Europe and Canada.</AbstractText></Abstract><AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Modi</LastName><ForeName>Ankita</ForeName><Initials>A</Initials><AffiliationInfo><Affiliation>Merck & Co., Inc., Kenilworth, New Jersey, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sen</LastName><ForeName>Shuvayu</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Merck & Co., Inc., Kenilworth, New Jersey, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Adachi</LastName><ForeName>Jonathan D</ForeName><Initials>JD</Initials><AffiliationInfo><Affiliation>St. Joseph's Healthcare and McMaster University, Hamilton, Ontario, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Adami</LastName><ForeName>Silvano</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Department of Medicine, University of Verona, Verona, Italy.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cortet</LastName><ForeName>Bernard</ForeName><Initials>B</Initials><AffiliationInfo><Affiliation>Department of Rheumatology, University Hospital of Lille, Lille Cedex, France.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Cooper</LastName><ForeName>Alun L</ForeName><Initials>AL</Initials><AffiliationInfo><Affiliation>Bridge Medical Centre Crawley, West Sussex, UK.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Geusens</LastName><ForeName>Piet</ForeName><Initials>P</Initials><AffiliationInfo><Affiliation>Department of Rheumatology, CAPHRI School for Public Health and Primary Care, Maastricht University, Maastricht, the Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Mellström</LastName><ForeName>Dan</ForeName><Initials>D</Initials><AffiliationInfo><Affiliation>Department of Internal Medicine and Geriatrics, Gothenburg University, Göteborg, Sweden.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Weaver</LastName><ForeName>Jessica P</ForeName><Initials>JP</Initials><AffiliationInfo><Affiliation>Merck & Co., Inc., Kenilworth, New Jersey, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>van den Bergh</LastName><ForeName>Joop P</ForeName><Initials>JP</Initials><AffiliationInfo><Affiliation>VieCuri Medical Centre, Venlo, The Netherlands.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Nguyen</LastName><ForeName>Allison M</ForeName><Initials>AM</Initials><AffiliationInfo><Affiliation>Merck & Co., Inc., Kenilworth, New Jersey, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Keown</LastName><ForeName>Paul A</ForeName><Initials>PA</Initials><AffiliationInfo><Affiliation>Syreon Corporation, Vancouver, Canada.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Leung</LastName><ForeName>Albert T</ForeName><Initials>AT</Initials><AffiliationInfo><Affiliation>Former employee of Merck & Co., Inc., Kenilworth, New Jersey, USA.</Affiliation></AffiliationInfo></Author><Author ValidYN="Y"><LastName>Sajjan</LastName><ForeName>Shiva</ForeName><Initials>S</Initials><AffiliationInfo><Affiliation>Merck & Co., Inc., Kenilworth, New Jersey, USA.</Affiliation></AffiliationInfo></Author></AuthorList><Language>eng</Language><PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType><PublicationType UI="D016448">Multicenter Study</PublicationType><PublicationType UI="D064888">Observational Study</PublicationType></PublicationTypeList><ArticleDate DateType="Electronic"><Year>2015</Year><Month>07</Month><Day>06</Day></ArticleDate></Article><MedlineJournalInfo><Country>Italy</Country><MedlineTA>Clin Exp Rheumatol</MedlineTA><NlmUniqueID>8308521</NlmUniqueID><ISSNLinking>0392-856X</ISSNLinking></MedlineJournalInfo><ChemicalList><Chemical><RegistryNumber>0</RegistryNumber><NameOfSubstance UI="D050071">Bone Density Conservation Agents</NameOfSubstance></Chemical></ChemicalList><CitationSubset>IM</CitationSubset><MeshHeadingList><MeshHeading><DescriptorName UI="D000368" MajorTopicYN="N">Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D050071" MajorTopicYN="Y">Bone Density Conservation Agents</DescriptorName><QualifierName UI="Q000008" MajorTopicYN="N">administration & dosage</QualifierName><QualifierName UI="Q000009" MajorTopicYN="N">adverse effects</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D002170" MajorTopicYN="N" Type="Geographic">Canada</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D015331" MajorTopicYN="N">Cohort Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D019468" MajorTopicYN="N">Disease Management</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005060" MajorTopicYN="N" Type="Geographic">Europe</DescriptorName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D005260" MajorTopicYN="N">Female</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D005767" MajorTopicYN="Y">Gastrointestinal Diseases</DescriptorName><QualifierName UI="Q000139" MajorTopicYN="N">chemically induced</QualifierName><QualifierName UI="Q000453" MajorTopicYN="N">epidemiology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D006801" MajorTopicYN="N">Humans</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D007391" MajorTopicYN="N">International Cooperation</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D055118" MajorTopicYN="N">Medication Adherence</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D008875" MajorTopicYN="N">Middle Aged</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D015663" MajorTopicYN="Y">Osteoporosis, Postmenopausal</DescriptorName><QualifierName UI="Q000175" MajorTopicYN="N">diagnosis</QualifierName><QualifierName UI="Q000188" MajorTopicYN="N">drug therapy</QualifierName><QualifierName UI="Q000523" MajorTopicYN="N">psychology</QualifierName></MeshHeading><MeshHeading><DescriptorName UI="D017060" MajorTopicYN="N">Patient Satisfaction</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D010818" MajorTopicYN="Y">Practice Patterns, Physicians'</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011446" MajorTopicYN="N">Prospective Studies</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011788" MajorTopicYN="Y">Quality of Life</DescriptorName></MeshHeading><MeshHeading><DescriptorName UI="D011795" MajorTopicYN="N">Surveys and Questionnaires</DescriptorName></MeshHeading></MeshHeadingList></MedlineCitation><PubmedData><History><PubMedPubDate PubStatus="received"><Year>2015</Year><Month>02</Month><Day>27</Day></PubMedPubDate><PubMedPubDate PubStatus="accepted"><Year>2015</Year><Month>04</Month><Day>14</Day></PubMedPubDate><PubMedPubDate PubStatus="entrez"><Year>2015</Year><Month>7</Month><Day>7</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="pubmed"><Year>2015</Year><Month>7</Month><Day>7</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate><PubMedPubDate PubStatus="medline"><Year>2015</Year><Month>10</Month><Day>3</Day><Hour>6</Hour><Minute>0</Minute></PubMedPubDate></History><PublicationStatus>ppublish</PublicationStatus><ArticleIdList><ArticleId IdType="pubmed">26146786</ArticleId><ArticleId IdType="pii">9246</ArticleId></ArticleIdList></PubmedData></pubmed><affiliations><list><country><li>Canada</li><li>France</li><li>Italie</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>Suède</li><li>États-Unis</li></country><region><li>Colombie-Britannique</li><li>New Jersey</li></region><settlement><li>Vancouver</li></settlement></list><tree><country name="États-Unis"><region name="New Jersey"><name sortKey="Modi, Ankita" sort="Modi, Ankita" uniqKey="Modi A" first="Ankita" last="Modi">Ankita Modi</name></region><name sortKey="Leung, Albert T" sort="Leung, Albert T" uniqKey="Leung A" first="Albert T" last="Leung">Albert T. Leung</name><name sortKey="Nguyen, Allison M" sort="Nguyen, Allison M" uniqKey="Nguyen A" first="Allison M" last="Nguyen">Allison M. Nguyen</name><name sortKey="Sajjan, Shiva" sort="Sajjan, Shiva" uniqKey="Sajjan S" first="Shiva" last="Sajjan">Shiva Sajjan</name><name sortKey="Sen, Shuvayu" sort="Sen, Shuvayu" uniqKey="Sen S" first="Shuvayu" last="Sen">Shuvayu Sen</name><name sortKey="Weaver, Jessica P" sort="Weaver, Jessica P" uniqKey="Weaver J" first="Jessica P" last="Weaver">Jessica P. Weaver</name></country><country name="Canada"><noRegion><name sortKey="Adachi, Jonathan D" sort="Adachi, Jonathan D" uniqKey="Adachi J" first="Jonathan D" last="Adachi">Jonathan D. Adachi</name></noRegion><name sortKey="Keown, Paul A" sort="Keown, Paul A" uniqKey="Keown P" first="Paul A" last="Keown">Paul A. Keown</name></country><country name="Italie"><noRegion><name sortKey="Adami, Silvano" sort="Adami, Silvano" uniqKey="Adami S" first="Silvano" last="Adami">Silvano Adami</name></noRegion></country><country name="France"><noRegion><name sortKey="Cortet, Bernard" sort="Cortet, Bernard" uniqKey="Cortet B" first="Bernard" last="Cortet">Bernard Cortet</name></noRegion></country><country name="Royaume-Uni"><noRegion><name sortKey="Cooper, Alun L" sort="Cooper, Alun L" uniqKey="Cooper A" first="Alun L" last="Cooper">Alun L. Cooper</name></noRegion></country><country name="Pays-Bas"><noRegion><name sortKey="Geusens, Piet" sort="Geusens, Piet" uniqKey="Geusens P" first="Piet" last="Geusens">Piet Geusens</name></noRegion><name sortKey="Van Den Bergh, Joop P" sort="Van Den Bergh, Joop P" uniqKey="Van Den Bergh J" first="Joop P" last="Van Den Bergh">Joop P. Van Den Bergh</name></country><country name="Suède"><noRegion><name sortKey="Mellstrom, Dan" sort="Mellstrom, Dan" uniqKey="Mellstrom D" first="Dan" last="Mellström">Dan Mellström</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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